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- Pathology Outlines - Stains CD markers
Immunostains, routine stains and CD markers at PathologyOutlines com
- Pathology Outlines - Adenoid cystic carcinoma
Typically p63 positive p40 negative, whereas adenoid cystic carcinoma is typically positive for both p63 and p40 (Am J Surg Pathol 2014;38:257) HPV related multiphenotypic sinonasal carcinoma: Also can affect sinonasal tract and show similar morphology and expression May have surface dysplasia Positive for high risk HPV; negative for MYB-NFIB
- Pathology Outlines - Squamous cell carcinoma
C p40 is the stain of choice for the identification of squamous cell carcinoma and will help demonstrate squamous differentiation Answers A and B are incorrect because while CK7 and CK5 6 would also both be positive in this lesion, they would not prove squamous differentiation, as they are positive in the majority of lung carcinomas
- Pathology Outlines - Small cell carcinoma
Positive for p40 and high molecular weight keratins, negative neuroendocrine markers (CD56, synaptophysin, chromogranin) Lung adenocarcinoma, poorly differentiated: Negative for neuroendocrine markers, diffuse strong CK7 Atypical carcinoid tumor: More prominent nucleoli, organoid growth pattern Large cell neuroendocrine carcinoma:
- Pathology Outlines - Biopsies
The tumor cells show variable p40 reactivity and are negative for both TTF1 and mucicarmine What is the best designation for this tumor? Non-small cell carcinoma, favor adenocarcinoma Non-small cell carcinoma, favor squamous cell carcinoma Non-small cell carcinoma, not otherwise specified Squamous cell carcinoma Squamous cell carcinoma
- HPV associated cervical squamous cell carcinoma
HPV associated cervical squamous cell carcinoma is an invasive epithelial tumor composed of neoplastic cells with varying degrees of squamous differentiation
- Pathology Outlines - Squamous cell carcinoma
Squamous cell carcinoma is the primary squamous cell carcinoma of anus
- Pathology Outlines - Basal cell carcinoma
Basal cell carcinoma arises from the interfollicular or follicular epithelium and is the most common malignant tumor type in humans
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