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- Urokinase - Wikipedia
Urokinase is encoded in humans by the PLAU gene, which stands for "plasminogen activator, urokinase" [7] The same symbol represents the gene in other animal species
- PLAU | Cancer Genetics Web
According to the survival analyses, PLAU and SERPINE1 could predict the overall survival of HNSCC patients from the TCGA cohort Multivariable Cox regression analyses showed that the PLAU and SERPINE1 were independent prognostic factors for HNSCC patients
- PLAU - an overview | ScienceDirect Topics
PLAU refers to the gene that encodes urokinase plasminogen activator, which is highly expressed in most prostate cancer tissues and invasive prostate cancer cell lines
- PLAU plasminogen activator, urokinase - NIH Genetic Testing . . .
These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA) HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA)
- Expression of PLAU in cancer - Summary - The Human Protein Atlas
Expression of PLAU (UPA, URK) in cancer tissue The cancer tissue page shows antibody staining of the protein in 20 different cancers
- The PLAU gene and its putative association with human ageing
PLAU is a protease that converts plasminogen to plasmin It appears to affect murine ageing: its overexpression in the brain diminishes food consumption and extends longevity probably through a mechanism similar to caloric restriction [13]
- Metastatic phenotype and immunosuppressive tumour . . .
Previous studies have revealed the role of dysregulated urokinase plasminogen activator (encoded by PLAU) expression and activity in several pathways associated with cancer progression
- Protein structure - PLAU - The Human Protein Atlas
Summary of RNA expression analysis and annotation data generated within the Human Protein Atlas project The RNA data was used to cluster genes according to their expression across single cell types
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