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  • Pathology Outlines - PRAME
    PRAME (preferentially expressed antigen in melanoma) is a cancer testis antigen expressed by melanoma and other malignant neoplasms with expression in normal tissue largely restricted to testis
  • What is PRAME? | MyPathologyReport
    PRAME stands for “preferentially expressed antigen in melanoma ” It is a special type of protein called a cancer-testis antigen This means that PRAME is usually found in cancer cells and normal cells within the testis, but rarely in other normal tissues of the body
  • PRAME - Wikipedia
    PRAME (preferentially expressed antigen of melanoma) is a protein that in humans is encoded by the PRAME gene [3][4][5] Five alternatively spliced transcript variants encoding the same protein have been observed for this gene
  • PRAME Expression in Melanocytic Tumors - PMC
    PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen that was isolated by autologous T cells in a melanoma patient
  • PRAME Updated: Diagnostic, Prognostic, and Therapeutic Role . . .
    Preferentially Expressed Antigen in Melanoma (PRAME), a member of the cancer testis antigen family, is central to the field of skin cancer diagnostics and therapeutics
  • PRAME Shows Promise as a Treatment Avenue in . . . - OncLive
    As investigators continue to refine and carve out a role for targeted therapies in the treatment paradigm across tumor types, preferentially expressed antigen in melanoma (PRAME) has emerged as
  • Immatics’ PRAME T-cell engager improves | ApexOnco - Clinical . . .
    Last year, Immatics failed to impress with its PRAME-targeting T-cell engager IMA402, but the company is back with updated phase 1 results that cast the project in a better light
  • Preferentially Expressed Antigen in Melanoma (PRAME . . .
    Preferentially expressed antigen in melanoma (PRAME) is a cancer-testis antigen that is minimally expressed in adult human tissues other than gonads but is present in various human cancers including melanoma and some sarcomas (1–6)


















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