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- Orforglipron, an oral GLP-1, cut HbA1c, weight at 40 weeks . . .
CHICAGO — Orforglipron, a novel nonpeptide, small molecule oral GLP-1, reduced HbA1c at 40 weeks for patients with type 2 diabetes, according to results of the phase 3 ACHIEVE-1 trial
- Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist . . .
Participants had type 2 diabetes treated only with diet and exercise, a glycated hemoglobin level of at least 7 0% but no more than 9 5%, and a body-mass index (the weight in kilograms divided by
- Lillys oral GLP-1, orforglipron, showed compelling efficacy . . .
The investigational once-daily pill lowered A1C by an average of 1 3% to 1 6% across doses, with improvements seen as early as four weeks, in adults with type 2 diabetes In ACHIEVE-1
- People With Severe Diabetes Are Cured in Small Trial of New Drug
Patients with type 1 must inject carefully calibrated doses of the hormone to substitute for the insulin their body is missing Type 1 is different from the more common type 2 diabetes, which usually occurs later in life Controlling insulin levels is a constant, often costly effort Elevated blood sugar levels can damage the heart, kidneys
- Eli Lilly’s Obesity Pill Appears to Work as Well as Injected . . .
The 40-week trial tested three doses of orforglipron—3 milligrams, 12 milligrams, and 36 milligrams—against a placebo in 559 patients with type 2 diabetes
- Novel Oral GLP-1 Agent Cuts A1c, Weight in Early Diabetes
CHICAGO -- An investigational, oral small-molecule GLP-1 receptor agonist improved glycated hemoglobin levels in adults with early-stage type 2 diabetes, a phase III randomized trial found
- Ozempic pill? Trial suggests new oral drug works as well as . . .
An experimental pill may work just as well as injectable, Ozempic-style drugs at treating type 2 diabetes, early trial results suggest
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