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- Protease mechanisms | Learn Science at Scitable - Nature
Protease mechanisms Polypeptides can be cleaved either chemically or enzymatically Enzymes that catalyse the hydrolytic cleavage of peptide bonds are called proteases Proteases fall into four
- Proteases - Latest research and news - Nature
Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids within proteins (known as proteolysis) Proteases can also remove protein post
- Serine Protease, Enzyme Catalysis | Learn Science at Scitable - Nature
The first serine protease scientists explored in detail was chymotrypsin, a digestive enzyme synthesized in our pancreas, along with the related enzymes trypsin and elastase It is transported to
- On the cutting edge: protease-based methods for sensing and . . . - Nature
Protease-based systems essentially use one of two mechanisms to sense upstream events: proximity-induced fragment complementation (of protease or, in the case of ubiquitin, of substrate) or
- Targeting proteases: successes, failures and future prospects
Proteases, also known as proteolytic enzymes, are enzymes that catalyse the breakdown of proteins by hydrolysis of peptide bonds Using bioinformatic analysis of the mouse and human genomes, at
- Substrate recognition and cleavage mechanism of the monkeypox protease . . .
The poxvirus core protease (CorePro) is essential for viral maturation and highly conserved in poxviruses, making it an attractive antiviral target1 However, the structure of CorePro remains
- Human and mouse proteases: a comparative genomic approach
For each single protease locus, a 500-kb genomic sequence flanking the target gene was analysed for the presence of further members of that family, as ∼ 23% of human and 34% of mouse protease
- A programmable protease-based protein secretion platform for . . . - Nature
A controllable protease-based protein secretion platform was developed for the rapid delivery of user-defined therapeutic protein secretion in response to FDA-approved drugs, tumor antigen and
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