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- Psychedelic and Dissociative Drugs | National Institute on Drug Abuse
Psychedelic and dissociative drugs can temporarily alter a person’s mood, thoughts, and perceptions of reality 1 Among other health effects and safety concerns, people who use psychedelic and dissociative drugs report feeling strong emotions, ranging from intense happiness and a feeling of connectedness to fear, anxiety, and confusion 2,3 People who use these drugs also report experiencing
- Psychedelic and Dissociative Drugs as Medicines
Psychedelic-assisted therapy—or ketamine-assisted therapy, if that substance is used—is when the use of psychedelic or dissociative drugs is integrated with other treatments, mainly talk therapy Though more research is needed, scientists theorize that these substances promote brain changes that have the potential to promote healthy thought
- Psilocybin (Magic Mushrooms) | National Institute on Drug Abuse
Learn more about NIDA research on the therapeutic potential of psychedelic and dissociative drugs, including psilocybin Along with other partners at the National Institutes of Health, NIDA is supporting research into psilocybin as a potential clinical treatment for substance use disorders and other mental illnesses
- Law enforcement seizures of psilocybin mushrooms rose dramatically . . .
Psilocybin mushrooms fall under a broader drug category known as psychedelic and dissociative drugs, which can temporarily alter a person’s mood, thoughts, and perceptions Self-reported data on the prevalence of their use is limited, though available research suggests that use of drugs like psilocybin that cause hallucinations has increased
- MDMA (Ecstasy Molly) | National Institute on Drug Abuse (NIDA)
MDMA, also called Molly or Ecstasy, is a lab-made (synthetic) drug that has effects similar to stimulants like methamphetamine, although some researchers and organizations consider MDMA to be a psychedelic drug because it can also mildly alter visual and time perception
- Drogas psicodélicas y disociativas | National Institute on Drug Abuse
Psychedelic Drug Legislative Reform and Legalization in the US JAMA Psychiatry Published online December
- Ketamine | National Institute on Drug Abuse (NIDA)
For more information on ketamine as a therapeutic substance, see “Psychedelic and dissociative drugs as medicines ” Is ketamine use increasing? There are many clinics across the United States now offering ketamine, sometimes in combination with talk therapy
- NIDA IC Fact Sheet 2025 | National Institute on Drug Abuse
designed to trap drugs, as well as psychedelic-based therapies to reset brain circuits underlying addiction Innovation and Entrepreneurship NIDA provided early funding to startups to tackle the overdose crisis in unique ways, such as by monitoring wastewater for patterns of drug use and providing SUD care by telehealth
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