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- Outcomes of a Pharmacological Protocol with Pentoxifylline . . .
Medication-related osteonecrosis of the jaws (MRONJ) is a challenging situation in clinics Previous studies have shown that pentoxifylline combined with tocopherol proved to be beneficial in patients with osteoradionecrosis, due to their
- Review - ScienceDirect
According to this literature review, observational and case-series studies have demonstrated that pentoxifylline and tocopherol are useful in non-invasive management of MRONJ PENTO protocol prescription was reported to be well tolerated, with minimal side-effects, and non-expensive when compared with other non-surgical treatment modalities
- Pentoxifylline and tocopherol protocol to treat medication . . .
Study design: A literature review was conducted, using two different scientific databases, to evaluate the effects of PTX and tocopherol on MRONJ Discussion: PENTO protocol prescription to treat MRONJ was reported to be well tolerated, with minimal side-effects, and non-expensive when compared with other non-surgical treatment modalities
- Prevention and treatment of osteonecrosis of the jaws using . . .
We report an evaluation of the association of Pentoxifylline-Tocopherol to reduce or to treat the side effects on jawbone of the antiresorptive medications Patients and methods: Six patients were selected two of them with intractable cases of MRONJ due to antiresorptive
- PENTOXIFYLLINE AND TOCOFEROL FOR MEDICATION-RELATED . . .
The PENTO protocol (pentoxifylline and tocopherol) has been reported in many studies for osteoradionecrosis, showing a significant improvement in bone recovery capacity However, few of those studies are related to MRONJ We report 11 cases of patients in oncologic treatment who presented MRONJ and were treated with the PENTO protocol
- Prevention and treatment of osteonecrosis of the jaws using . . .
Results: following the prescription of pentoxifylline -tocopherol, to prevent the occurrence of an MRONJ or to protect the surgical procedure for surgical removal of necrotic exposed bone, at the
- Pharmacological Treatment of Medication-Related Osteonecrosis . . .
Conclusions: Pentoxifylline and tocopherol therapy in MRONJ was effective in patients taking oral and intravenous bisphosphonates, in patients with osteoporosis, and undergoing oncological treatment This treatment approach allows surgery to be avoided or significantly reduced
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