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- Sex-determining region Y protein - Wikipedia
Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placentals and marsupials) [5]
- SRY gene - MedlinePlus
The SRY gene provides instructions for making a protein called the sex-determining region Y protein This protein is involved in male-typical sex development, which usually follows a certain pattern based on an individual's chromosomes People usually have 46 chromosomes in each cell
- SRY: Sex determination - Genes and Disease - NCBI Bookshelf
SRY (which stands for sex-determining region Y gene) is found on the Y chromosome In the cell, it binds to other DNA and in doing so distorts it dramatically out of shape This alters the properties of the DNA and likely alters the expression of a number of genes, leading to testis formation
- SRY Gene: A Comprehensive Guide to the Sex-Determining Factor . . .
Located on the Y chromosome, the SRY gene is primarily expressed in the cells of the developing gonads Its expression triggers a cascade of molecular events that lead to the development of testes instead of ovaries This gene acts as the master regulator of male sexual development
- SRY Gene - GeneCards | SRY Protein | SRY Antibody
SRY (Sex Determining Region Y) is a Protein Coding gene Diseases associated with SRY include 46,Xx Sex Reversal 1 and 46,Xy Sex Reversal 1 Among its related pathways are Mammalian disorder of sexual development and Signaling by WNT
- Sex-determining Region Y in Mammals | Embryo Project Encyclopedia
The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes, such as testes The Sry gene, located on the short branch of the Y chromosome, initiates male embryonic development in the XY sex determination system
- SRY Gene - an overview | ScienceDirect Topics
SRY is a single exon gene located on the short arm of the Y chromosome and is the “testis determining factor ” SRY gene mutations generally result in complete gonadal dysgenesis (CGD) and sex reversal
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