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- Sacituzumab govitecan - Wikipedia
Sacituzumab govitecan is a Trop-2-directed antibody and topoisomerase inhibitor drug conjugate, meaning that the drug targets the Trop-2 receptor that helps the cancer grow, divide and spread, and is linked to topoisomerase inhibitor, which is a chemical compound that is toxic to cancer cells [11]
- For adult patients | TRODELVY® (sacituzumab govitecan-hziy)
Discover TRODELVY® (sacituzumab govitecan‐hziy) for treatment guidance, clinical trial results, addressing side effects, and patient support services See Important Facts Important Warning
- Sacituzumab govitecan - Drugs. com
Sacituzumab govitecan is a targeted antibody-drug conjugate (ADC) designed to deliver anticancer medicine directly into cells with Trop-2 proteins Research has found that certain types of cancer cells contain more Trop-2 protein than noncancerous cells
- Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
In this randomized, phase 3 trial, we evaluated sacituzumab govitecan as compared with single-agent chemotherapy of the physician’s choice (eribulin, vinorelbine, capecitabine, or gemcitabine) in
- Trodelvy: What to Expect, Side Effects, and More
Trodelvy is used to treat some HER2-negative breast cancers Trodelvy (chemical name: sacituzumab govitecan-hziy) is a targeted therapy medication called an antibody-drug conjugate (ADC) that targets a protein found on the surface of cancer cells
- FDA approves sacituzumab govitecan-hziy for HR-positive breast cancer
On February 3, 2023, the Food and Drug Administration (FDA) approved sacituzumab govitecan-hziy (Trodelvy, Gilead Sciences, Inc ) for patients with unresectable locally advanced or metastatic
- Sacituzumab Govitecan-hziy - NCI - National Cancer Institute
Sacituzumab govitecan-hziy is a type of targeted therapy drug called an antibody-drug conjugate It consists of a monoclonal antibody linked to a toxic drug called SN-38 that binds to a protein on the surface of some cancer cells
- Sacituzumab govitecan-hziy (intravenous route) - Mayo Clinic
Sacituzumab govitecan-hziy injection is used to treat triple-negative breast cancer that has spread (metastatic) or cannot be removed by surgery (unresectable locally advanced)
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