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- Semaglutide - ALZFORUM
Semaglutide is a synthetic, long-acting analog of glucagon-like peptide-1, used to treat diabetes Ozempic TM is a once-per-week injection formulation, while Rybelsus TM is is a daily pill
- Novel LC-MS MS analysis of the GLP-1 analog semaglutide with its . . .
Lee TS, Park EJ, Choi M, Oh HS, An Y, Kim T, Kim TH, Shin BS, Shin S Novel LC-MS MS analysis of the GLP-1 analog semaglutide with its application to pharmacokinetics and brain distribution studies in rats J Chromatogr B Analyt Technol Biomed Life Sci 2023 Apr 15;1221:123688 Epub 2023 Mar 22 PubMed
- Exploring the Impact of Semaglutide on Cognitive Function and Anxiety . . .
Boboc IK, Dumitrelea PD, Meca AD, Mititelu-Tartau L, Bogdan M Exploring the Impact of Semaglutide on Cognitive Function and Anxiety-Related Behaviors in a Murine Model of Alzheimer's Disease
- ALZFORUM | NETWORKING FOR A CURE
The compound curbs appetite, possibly by cooling inflammation in the hypothalamus Mice on TN-783 and the glucagon-like peptide 1 (GLP-1) mimetic semaglutide dropped those stubborn last grams that wouldn’t come off on semaglutide alone
- Semaglutide Attenuates Anxious and Depressive-Like Behaviors and . . .
Semaglutide Attenuates Anxious and Depressive-Like Behaviors and Reverses the Cognitive Impairment in a Type 2 Diabetes Mellitus Mouse Model Via the Microbiota-Gut-Brain Axis
- NT-0796 | ALZFORUM
In diet-induced obesity in these mice, NT-0796 caused weight loss as potently as did the GLP1 inhibitor semaglutide, and improved markers of cardiovascular risk (Thornton et al , 2024)
- Semaglutide is Neuroprotective and Reduces α-Synuclein Levels in the . . .
Zhang L, Zhang L, Li L, Hölscher C Semaglutide is Neuroprotective and Reduces α-Synuclein Levels in the Chronic MPTP Mouse Model of Parkinson's Disease J Parkinsons Dis 2019;9 (1):157-171
- Liraglutide - ALZFORUM
Background Liraglutide is an analog of glucagon-like peptide 1 GLP-1 is a hormone that is produced in the gut and activates receptors in the gut, liver, and pancreas to control blood-sugar levels and reduce insulin resistance Liraglutide and related GLP-1 mimetics cause body weight loss and reduce the risk of cardiovascular events, stroke, and dementia in people with diabetes
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