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- Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
Sickle cell disease affects more than 100,000 people in the United States and 8 million people worldwide In the United States, 9 of 10 people who have sickle cell disease are of African ancestry or identify as Black: About 1 in 13 Black babies are born with sickle cell trait,meaning that they inherited a sickle cell gene from one parent
- Sickle Cell Disease - Causes and Risk Factors - NHLBI, NIH
This child has sickle cell trait and is a carrier of the gene for hemoglobin S A 25%, or 1 in 4, chance of inheriting two copies of the gene for hemoglobin S This child has sickle cell disease A child with sickle cell disease may also have one copy of the gene for hemoglobin S and one copy of a gene for another faulty hemoglobin
- Sickle Cell Disease - Symptoms - NHLBI, NIH
Serious symptoms of sickle cell disease are emergencies and need treatment right away Seek care or call 9-1-1 if you or someone else is experiencing: Severe pain A serious pain event is sometimes called a “pain crisis,” “sickle cell crisis,” or “vaso-occlusive crisis ” Most people with sickle cell disease have this often-serious pain
- What is Sickle Cell Trait? Fact Sheet - NHLBI, NIH
Sickle cell trait occurs when a person has one copy of the sickle cell gene passed down from one parent, and a normal hemoglobin gene from the other parent This fact sheet describes what sickle cell trait is, who is affected, how to know if you have it, and how to live well with sickle cell trait
- Enfermedad de Células Falciformes (Sickle cell disease)
(Sickle cell disease (SCD) is the most common inherited blood disorder in the United States In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD ) Print Length:
- September is National Sickle Cell Awareness Month
Share the resources below to help people Get to Know Sickle Cell, including common symptoms, how it’s diagnosed and managed, and advancements in research and treatment options You can also find real stories of people affected by sickle cell disease Read the Proclamation on National Sickle Cell Awareness Month 2024
- Sickle Cell Genetics and Pathophysiology | NHLBI, NIH
To participate in this study, you must be at least 2 years old with known or suspected sickle cell disease, sickle cell trait, or other red blood cell disorders Participants will have a physical exam and receive standard medical care for sickle cell disease, including routine follow-up tests and procedures
- Sickle Cell Branch - NHLBI, NIH
A crucial difference between these conditions is that beta thalassemia results from a reduced number of red blood cells, while sickle cell disease results from abnormal sickle hemoglobin, or HbS, that makes red blood cells rigid and sickle-shaped, causing acute intermittent pain due to blockages of blood vessels and interruption of oxygen
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