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- Terminal deoxynucleotidyl transferase - Wikipedia
Terminal deoxynucleotidyl transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia lymphoma cells
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- Pathology Outlines - TdT
TdT is a nuclear marker expressed in most precursor lymphoid neoplasms; it is a member of the X family of DNA polymerases and is encoded by DNTT on 10q24 1i
- Terminal Transferase - NEB
Terminal transferase (TdT) is a template independent polymerase that catalyzes the addition of deoxynucleotides to the 3' hydroxyl terminus of DNA molecules Protruding, recessed or blunt-ended double or single-stranded DNA molecules serve as a substrate for TdT
- Terminal Deoxynucleotidyl Transferase: The Story of a Misguided DNA . . .
Our discussion begins by examining the biological role of TdT and how synthesizing DNA without using a templating strand is important for V (D)J recombination Attention will then focus on understanding the molecular mechanism by which TdT performs template-independent polymerization
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