PCSK9 Inhibitors vs. Statins for High Cholesterol - GoodRx PCSK9 inhibitors are injectable cholesterol medications that you administer once or twice a month Statins are oral medications that you take every day Both classes work differently to lower cholesterol and can be prescribed together Statins are considered first-choice treatments for high cholesterol
Understanding Cholesterol Therapy: An Update for Community Pharmacists PCSK9 Inhibitors Approved by the FDA in July 2015 and August 2015, respectively, Praluent (alirocumab) and Repatha (evolocumab) are monoclonal antibodies that inhibit PCSK9 14,15 PCSK9 binds to LDL receptors on the surface of hepatocytes, thereby degrading the LDL receptor
PCSK9 inhibitors and ezetimibe with or without statin therapy for . . . Statins are recommended as first-line drugs for cardiovascular risk reduction; ezetimibe and proprotein convertase subtilisn kexin type 9 (PCSK9) inhibitors are recommended as add-on therapies if patients require further cardiovascular risk reduction
List of PCSK9 inhibitors - Drugs. com What are PCSK9 inhibitors? Proprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme that binds to low-density lipoprotein receptors (LDL receptors), which stops LDL being removed from the blood, leading to an increase in blood levels of LDL
What Is Ezetimibe (Zetia) and How Does It Lower Cholesterol? PCSK9 inhibitors are a newer class of cholesterol-lowering drugs that increase the liver's ability to remove LDL-C from the blood They are usually reserved for patients with very high cholesterol levels or those who cannot achieve their targets with statins and ezetimibe