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- TNF receptor associated factor - Wikipedia
TNF receptor associated factors (TRAFs) are a family of proteins primarily involved in the regulation of inflammation, antiviral responses and apoptosis [1] Currently, seven TRAF proteins have been characterized in mammals: TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6 and TRAF7
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- Inflammation and cancer cell survival: TRAF2 as a key player
TNF receptor-associated factors (TRAFs) are key mediators in the intricate interplay between cancer and inflammation, making them promising therapeutic targets TRAFs belong to the TRAF
- TRAF Family Molecules in T cells: Multiple Receptors and Functions
The TNFR superfamily of receptors, the major focus of the recent TNFR Superfamily Conference held in June 2019, employ the TRAF family of adaptor proteins in key aspects of their signaling pathways
- Editorial: TRAF Proteins in Health and Disease - Frontiers
TRAF proteins are a family of signaling adaptors that play diverse roles in signaling by a broad range of receptors involved in immunity and inflammation
- TRAF1 from a Structural Perspective - MDPI
Tumor necrosis factor receptor-associated factor (TRAF) proteins play pivotal roles in a multitude of cellular signaling pathways, encompassing immune response, cell fate determination, development, and thrombosis
- Physiological Roles and Mechanisms of Signaling by TRAF2 and TRAF5
The TRAF domain mediates receptor binding, interactions with a number of adapter and signaling molecules, self association, and interactions with other TRAF proteins
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