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- Transthyretin - Wikipedia
Transthyretin (TTR or TBPA) is a transport protein in the plasma and cerebrospinal fluid that transports the thyroid hormone thyroxine (T 4) and retinol to the liver This is how transthyretin gained its name: trans ports thy roxine and retin ol
- Transthyretin Amyloidosis (ATTR-CM): Types, Causes, Treatment
Transthyretin amyloidosis (ATTR-CM) occurs when your liver produces faulty transthyretin (TTR) proteins Clumps of these abnormal proteins (called fibrils) build up in your heart’s main pumping chamber
- Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Transthyretin (trans-thy-re-tin) amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed and potentially fatal disease of the heart muscle In ATTR-CM, a protein called transthyretin that normally circulates in the bloodstream becomes misshapen and builds up in the heart, nerves and other organs
- A Narrative Review of the Role of Transthyretin in Health and Disease
Transthyretin is a highly conserved protein that transports the thyroid hormone thyroxine and the retinol-binding protein bound to retinol (vitamin A) Mutations in TTR are associated with ATTR amyloidosis, a progressive, debilitating, and ultimately fatal disease
- A Narrative Review of the Role of Transthyretin in Health and . . . - PubMed
Transthyretin (TTR) is a tetrameric transport protein highly conserved through vertebrate evolution and synthesized in the liver, choroid plexus, and retinal pigment epithelium TTR transports the thyroid hormone thyroxine and the retinol-binding protein (RBP) bound to retinol (vitamin A)
- Transthyretin | definition of transthyretin by . . . - Medical Dictionary
A protein component of plasma having a molecular weight of about 55,000 and containing 1 3% carbohydrate; estimated plasma concentration is 0 3 g per 100 mL; abnormal levels of prealbumin are found in cases of familial amyloidosis Synonym (s): transthyretin 2
- Transthyretin - an overview | ScienceDirect Topics
Transthyretin is a 55,000-Dalton protein that is synthesized primarily in the liver, and serves as the primary serum transport protein for holo-retinol-binding protein and a minor transport protein for thyroxine
- Transthyretin Amyloid Cardiomyopathy (ATTR-CM) - WebMD
ATTR-CM is a disease that makes the heart stiff and weak It happens when faulty proteins build up, which makes it harder to pump blood throughout the body This can lead to heart failure if left
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