安裝中文字典英文字典辭典工具!
安裝中文字典英文字典辭典工具!
|
- Kanamycin: Uses, Interactions, Mechanism of Action - DrugBank Online
Mechanism of action Aminoglycosides like kanamycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA Specifically Kanamycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12 This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit
- A study on the structure, mechanism, and biochemistry of kanamycin B . . .
Biosynthesis of kanamycin involves an oxidative deamination step catalyzed by kanamycin B dioxygenase (KanJ), thereby the C2’ position of kanamycin B is transformed into a keto group upon release of ammonia
- Kanamycin - an overview | ScienceDirect Topics
Kanamycin's mode of action is like that of streptomycin in that it causes a misreading of the genetic code, interacts with the 30s ribosomal subunit at many sites, and suppresses protein synthesis Miscoding is caused by all aminoglycoside antibiotics that have a 2-deoxystreptamine group
- Kanamycin: Package Insert Prescribing Info - Drugs. com
Mechanism of Action Kanamycin, an aminoglycoside, acts by inhibiting the synthesis of protein in susceptible microorganisms It is bactericidal in vitro against Gram-negative bacteria and certain Gram-positive bacteria
- Kanamycin - BioPharma Notes
Figure- mechanism of action of kanamycin is like other aminoglycosides (Source- Lippincott’s illustrated Reviews) Kanamycin and other aminoglycoside antibiotics diffuse through porin channels of gram-negative bacteria and enter periplasmic space
- The mechanism of action of kanamycin. [A] The normal translation . . .
[A] The normal translation process in a ribosome [B] After kanamycin (K) irreversibly binds to the 16S rRNA receptor in the 30S ribosomal subunit, the translation of the mRNA codons into
- How kanamycin A interacts with bacterial and mammalian mimetic . . .
Kanamycin A belongs to the family of aminoglycoside antibiotics that target cellular RNA to inhibit bacterial and viral replication Previous studies have shown that aminoglycosides bind to mammalian but disrupt bacterial membranes
|
|
|