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  • What causes Down syndrome? | NICHD - NICHD - Eunice Kennedy Shriver . . .
    Down syndrome is caused by a random error in cell division that results in the presence of an extra copy of chromosome 21 The type of error is called nondisjunction Usually when one cell divides in two, pairs of chromosomes are split so that one of the pair goes to one cell and the other from the pair goes to the other cell
  • Down syndrome - Symptoms and causes - Mayo Clinic
    Down syndrome is a genetic condition caused when an unusual cell division results in an extra full or partial copy of chromosome 21 This extra genetic material causes the developmental changes and physical features of Down syndrome The term "syndrome" refers to a set of symptoms that tend to happen together
  • Down Syndrome | Birth Defects | CDC - Centers for Disease Control and . . .
    Etiology of Down syndrome: Evidence for consistent association among altered meiotic recombination, nondisjunction, and maternal age across populations Am J Med Genet A 2009 Jul;149A(7):1415-20 Sherman SL, Allen EG, Bean LH, Freeman SB
  • Down Syndrome: Symptoms Causes - Cleveland Clinic
    Down syndrome is a genetic condition where a person is born with an extra copy of chromosome 21 This means that they have a total of 47 chromosomes instead of 46 This can affect how their brain and body develop People diagnosed with Down syndrome have happy and healthy lives with supportive care Down syndrome can affect how your child develops
  • Down syndrome - Wikipedia
    Down syndrome or Down's syndrome, [12] also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21 [3] It is usually associated with developmental delays, mild to moderate intellectual disability, and characteristic physical features [1][13]
  • Down Syndrome: Causes, Symptoms, Diagnosis, and Treatment - WebMD
    Down syndrome is a genetic condition that causes mild to significant physical and developmental problems People with Down syndrome (DS) are born with an extra chromosome
  • Down Syndrome: Causes, Types, and Symptoms - Healthline
    Down syndrome (sometimes called Down’s syndrome) is a condition in which a child is born with an extra copy of their 21st chromosome — hence its other name, trisomy 21 This causes
  • Down Syndrome (Trisomy 21) - Pediatrics - MSD Manuals
    Down syndrome is an abnormality of chromosome 21 that can cause intellectual disability, microcephaly, short stature, and characteristic facies Diagnosis is suggested by physical anomalies and abnormal development and confirmed by cytogenetic analysis Management depends on specific manifestations and anomalies


















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