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- Vesicant irritant chemotherapy | HemOnc. org - A Hematology Oncology Wiki
In order from most likely to least likely to cause damage when extravasation occurs: vesicants (most likely), exfoliants, irritants, inflammitants, and neutrals (least likely) Some references primarily classify drugs as vesicants or irritants, so those categories will preferentially be used below over classifying as inflammitants and exfoliants
- Blister agent - Wikipedia
Blister agents are named for their ability to cause large, painful water blisters on the bodies of those affected A blister agent (or vesicant) is a chemical compound that causes severe skin, eye and mucosal pain and irritation in the form of severe chemical burns resulting in fluid filled blisters [1]
- Vesicants | CTTL | CDC - Centers for Disease Control and Prevention
Vesicants, or "blister agents," are human-made chemical warfare agents that cause blistering of the skin and mucous membranes on contact These agents can be spread as a liquid, gas, or spray, and they cause damage by direct contact with skin, eyes, and the pathway from the nose and mouth to the lungs
- VESICANTS, CHEMOTHERAPEUTIC AGENTS AND VASCULAR ACCESS RECOMMENDATIONS
A vesicant is any agent that has the potential to cause blistering, severe tissue damage or necrosis when extravasated The Pharmacist will evaluate patients on a case-by-case basis when orders are received for a vesicant May be given by peripheral vein but are BEST administered by central vein
- Vesicants and Extravasation - Infusion Nurse Blog
Vesicant – an agent capable of causing blistering, tissue sloughing or necrosis when it escapes from the intended vascular pathway into surrounding tissue Extravasation – the inadvertent infiltration of vesicant solution or medication into surrounding tissue
- What are Vesicants? - AZoLifeSciences
Vesicants are cytotoxic alkylating compounds A classic example of a vesicant is mustard or mustard gas However, blistering agents include sulfur mustard, nitrogen mustard, lewisite, and phosgene oxime Vesicants inhibit cell division and decrease tissue respiration, leading to cell death
- Vesicant Chemical-Warfare Agents - The Merck Manuals
Vesicants are chemical-warfare agents that cause blistering (vesicles) and include These agents also affect the respiratory tract: mustards are predominantly type 1 agents, which affect the large airways, phosgene oxime is a type 2 agent, which affects the lower airways and alveoli, and Lewisite is a mixed agent
- What are vesicant drugs? – MassInitiative
Vesicants are IV solutions and medications that cause ischemia and necrosis Vesicants are extremely acidic or basic (pH less than 5 or greater than 9), hyperosmolar (extremely concentrated), or vasoconstrictive (cause the blood vessels to constrict)
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