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- Vesicant irritant chemotherapy - HemOnc. org
Some medications are more likely to have vesicant properties in high concentrations or large volumes In order from most likely to least likely to cause damage when extravasation occurs: vesicants (most likely), exfoliants, irritants, inflammitants, and neutrals (least likely)
- Blister agent - Wikipedia
Blister agents are named for their ability to cause large, painful water blisters on the bodies of those affected A blister agent (or vesicant) is a chemical compound that causes severe skin, eye and mucosal pain and irritation in the form of severe chemical burns resulting in fluid filled blisters [1]
- VESICANTS, CHEMOTHERAPEUTIC AGENTS AND VASCULAR ACCESS RECOMMENDATIONS
Vesicants should be given by central vein A vesicant is any agent that has the potential to cause blistering, severe tissue damage or necrosis when extravasated
- Extravasation injury from cytotoxic and other noncytotoxic vesicants in . . .
Drugs can be harmful when directly exposed to tissues, especially those classified as vesicants, which have the potential to cause severe tissue damage with lasting injury
- What are Vesicants? - AZoLifeSciences
Vesicants are cytotoxic alkylating compounds A classic example of a vesicant is mustard or mustard gas However, blistering agents include sulfur mustard, nitrogen mustard, lewisite, and phosgene oxime Vesicants inhibit cell division and decrease tissue respiration, leading to cell death
- Understanding Vesicant Drugs and Extravasation
Vesicants are a class of drugs known for their potential to cause tissue damage if they leak out of the vein into surrounding tissue Common vesicant agents include certain chemotherapy drugs (e g , doxorubicin, vincristine), antibiotics (e g , vancomycin), and other medications like potassium chloride and calcium chloride
- Irritants and vesicants: ensuring safe IV therapy - BD IV News
The potential effect of irritants and vesicants in infusates is a key consideration in identifying the appropriate VAD Download our guide to learn more
- Development of an Evidence-Based List of Non-Antineoplastic Vesicants
Infiltration of a vesicant, called extravasation, can result in severe patient injuries Recognition of vesicants and their relative risk of injury is essential to extravasation prevention, early recognition, and appropriate treatment
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