安裝中文字典英文字典辭典工具!
安裝中文字典英文字典辭典工具!
|
- YAP - Hippo 信号转导通路的介导物 | Cell Signaling Technology
YAP（Yes 相关蛋白，YAP65）是一种转录共激活蛋白，可用作 Hippo 抑癌基因通路的主要效应子。 通过 YAP 进行的 Hippo 信号转导在某种程度上可调控干细胞和祖细胞的增殖活性，从而调控组织生长和器官大小。
- 经典信号通路总结——Hippo信号通路 - 知乎
Hippo信号通路 由一组保守的激酶构成，是一条抑制细胞生长的信号通路。 在哺乳动物中，Hippo信号通路上游的膜蛋白受体感受到胞外环境的生长抑制信号后，经过一系列激酶的磷酸化反应，最终作用于下游效应因子 YAP 和 TAZ。
- Nature 正刊丨YAP TAZ在机械转导中的作用_细胞_Rho_调节
本研究揭示了YAP TAZ在细胞感知物理微环境中的重要作用，定义了一种新的YAP TAZ调节模式，即通过Rho活性和肌动蛋白细胞骨架的张力来调节，而非依赖Hippo通路。
- YAP1 Gene - GeneCards | YAP1 Protein | YAP1 Antibody
Recommended Yes-Associated Protein 1 (YAP1) (AA 1-504) protein (GST tag) Yes-Associated Protein 1 (YAP1) (AA 1-504) protein (His tag) Santa Cruz Biotechnology (SCBT) Antibodies for YAP1 YAP (63 7) YAP (H-9) Santa Cruz Biotechnology (SCBT) siRNA for YAP1 YAP siRNA (h) Santa Cruz Biotechnology (SCBT) CRISPR for YAP1
- Yes 相关蛋白 | Yes-associated protein (YAP) | MCE
Yes-associated protein (YAP) is a key transcription factor in the Hippo signaling pathway YAP is an oncoprotein located in the cytoplasm in an inactive form, and when activated, it translocates to the nucleus and activates the transcription of genes responsible for cell division and apoptosis
- Hippo信号通路：YAP和TAZ作用机制-酶联生物 - 知乎
YAP和TAZ继而与细胞骨架蛋白相互作用，被滞留在胞质内，不能进入细胞核行使其转录激活功能，从而实现对器官大小和体积的调控。
- YAP1 - Wikipedia
Mouse models with YAP over-expression have been shown to exhibit up-regulation of the TEAD target gene expression which results in increased expansion of progenitor cells and tissue overgrowth
- YAP maintains the dynamics of TDP-43 condensates and . . . - Nature
Our findings highlight an unexpected role of YAP in managing ALS-associated biomolecular condensates, presenting important implications for potential ALS treatments
|
|
|