安裝中文字典英文字典辭典工具!
安裝中文字典英文字典辭典工具!
|
- The multiple functions of protein phosphatase 6 - ScienceDirect
As discussed below, PP6 regulates DNA-PK activation, and BRCA1 affects PP6 signaling through its interaction with Ankrd28, it is possible that dysregulation of DNA-PK Chk2 BRCA1 signaling is involved in abnormal mitosis by PP6 deficiency
- The multiple functions of protein phosphatase 6 - PubMed
This review presents the accumulating evidence for the roles of protein phosphatase 6 (PP6) in cell cycle, DNA damage repair, inflammatory signaling, lymphocyte development, virus infection, tumor formation progression, cell tissue size, and non-coding RNA-mediated regulation
- Protein phosphatase 6 is a key factor regulating spermatogenesis
Protein phosphatase 6 (PP6) is a member of the PP2A-like subfamily, which plays a critical role in many fundamental cellular processes We recently reported that PP6 is essential for female
- PPP6C - Serine threonine-protein phosphatase 6 catalytic subunit - Homo . . .
Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS) (PubMed: 18186651)
- PP6 Regulatory Subunit R1 Is Bidentate Anchor for Targeting Protein . . .
DNA·PK complexes with the regulatory subunit SAPSR1 (R1) of protein phosphatase-6 (PP6) Knockdown of either R1 or PP6c prevents DNA-PK activation in response to ionizing radiation-induced DNA damage and radiosensitizes glioblastoma cells
- Protein Phosphatase 6 Complex: Novel Regulator of Fetal Hemoglobin and . . .
PPP6C is the catalytic subunit of protein phosphatase 6 (PP6), a serine threonine phosphatase complex that has been implicated in cell cycle regulation, autophagy, and innate immunity mechanisms in other cell types, but its role in erythropoiesis and HbF regulation has not previously been described
- Protein phosphatase 6 activates NF-κB to confer sensitivity to MAPK . . .
Inhibitors of the Ras-MAPK pathway are used to treat cancers carrying RAS and BRAF mutations Zhang et al performed a CRISPR-based screen to find modulators of the MAPK pathway and found that protein phosphatase 6 (PP6) increased sensitivity to MAPK pathway inhibitors
- Depletion of Ppp6c in hematopoietic and vascular endothelial cells . . .
Protein phosphatase 6 (PP6) is a serine threonine (Ser Thr) protein phosphatase, and its catalytic subunit is Ppp6c PP6 forms the PP2A subfamily with PP2A and PP4
|
|
|