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- SLC7A11 xCT antibody (26864-1-AP) | Proteintech - ptglab
SLC7A11 (also known as xCT) is a membrane transporter involved in the uptake of cystine It promotes glutathione synthesis through the uptake of cystine and the concomitant release of glutamate This, in turn, protects cells from oxidative stress, maintains cellular redox balance, and prevents cell death induced by lipid peroxidation
- SLC7A11 Gene - GeneCards | XCT Protein | XCT Antibody
SLC7A11 (Solute Carrier Family 7 Member 11) is a Protein Coding gene Diseases associated with SLC7A11 include Lysinuric Protein Intolerance and Brain Edema Among its related pathways are Nuclear events mediated by NFE2L2 and Transport of inorganic cations anions and amino acids oligopeptides
- SLC7A11 expression level dictates differential responses to oxidative . . .
The cystine transporter solute carrier family 7 member 11 (SLC7A11; also called xCT) protects cancer cells from oxidative stress and is overexpressed in many cancers
- SLC7A11 solute carrier family 7 member 11 [ Homo sapiens (human) ]
In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells
- xCT (SLC7A11)-mediated metabolic reprogramming promotes non . . . - Nature
Our results demonstrated that 1) xCT was highly expressed at the cytoplasmic membrane in non-small cell lung cancer (NSCLC), 2) the expression of xCT was correlated with advanced stage and
- xCT, not just an amino-acid transporter: a multi-functional regulator . . .
Expression of xCT, a component of the x c– amino-acid transporter, is essential for the uptake of cystine required for intracellular glutathione (GSH) synthesis and maintenance of the intracellular redox balance
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