IgA nephropathy (Berger disease) - Symptoms and causes IgA nephropathy (nuh-FROP-uh-thee), also known as Berger disease, is a kidney disease It happens when a germ-fighting protein called immunoglobulin A (IgA) builds up in the kidneys
IgA Nephropathy (Berger Disease): Symptoms Treatment - Cleveland Clinic IgA nephropathy, or Berger’s disease, is a kidney disease in which IgA antibodies build up abnormally Over time, it leads to kidney damage or kidney failure Symptoms include blood in your pee, swelling and flank pain
IgA Nephropathy (Berger Disease) - StatPearls - NCBI Bookshelf Immunoglobulin A (IgA) nephropathy, or IgAN, also known as Berger disease, is one of the leading causes of glomerulonephritis and renal failure This disease is a prevalent form of glomerulonephritis characterized by the deposition of IgA in the glomerular basement membrane
IgA Nephropathy (IgAN) | National Kidney Foundation IgA nephropathy (IgAN) is a type of kidney disease where antibodies build up in your kidneys and cause damage to your glomeruli (small filters inside your kidneys) Antibodies are a type of protein made by your immune system to protect against things like bacteria and viruses
IgA Nephropathy - NIDDK What is immunoglobulin A (IgA) nephropathy? IgA nephropathy is an autoimmune disease that occurs when clumps of antibodies are deposited in your kidneys, causing inflammation and kidney damage
IgA nephropathy: Update on pathogenesis and treatment The pathogenesis of immunoglobulin (Ig) A nephropathy is described through a “4-hit” model involving production of galactose-deficient IgA, production of autoantibodies to galactose-deficient IgA, and subsequent deposition of immune complexes in the kidney glomerulus Diagnosis remains dependent on a kidney biopsy, often after hematuria or proteinuria is detected on urinalysis
IgA nephropathy (Berger’s disease) – MyPathologyReport IgA nephropathy, also known as Berger’s disease, is a kidney condition characterized by the accumulation of immunoglobulin A (IgA) in the kidneys Antibodies are proteins that normally help fight infections However, in IgA nephropathy, abnormal forms of IgA accumulate in the kidneys, causing inflammation and damage This inflammation can eventually lead to kidney problems, including reduced
Immunoglobulin A (IgA) Nephropathy | Johns Hopkins Medicine What is IgA nephropathy? IgA nephropathy is a chronic kidney disease It progresses over 10 to 20 years, and it can lead to end-stage renal disease It is caused by deposits of the protein immunoglobulin A (IgA) inside the filters (glomeruli) in the kidney