Nanomodulators targeting endothelial WNT and pericytes to reversibly . . . Here, we proposed nitazoxanide (NTZ) and ibrutinib (IBR) co-loaded ICAM-1-targeting nanoparticles (NI@I-NPs) to disrupt the BTB in a time-dependent, reversible, and size-selective manner by targeting specific ICAM-1, inactivating WNT signaling and depleting pericytes in tumor-associated blood vessels in breast cancer brain metastases
MiR-15p-5p Mediates the Coordination of ICAM-1 and FAK to . . . - Springer Co-transfection of ICAM-1 and miR-15b-5p mimic inhibited the proliferation of bEnd 3 cells and decreased endothelial cell activity compared with transfection of ICAM-1 alone Moreover, co-transfection of miR-15b-5p mimic and FAK promoted cell proliferation and increased the activity of endothelial cells compared with transfection of the miR-15b
bEnd. 3 [BEND3] - CRL-2299 - ATCC The expression of Peyer's Patch high endothelial receptor for lymphocytes, the mucosal vascular addressin (MAdCAM-1) and E-selectin can be induced on bEnd 3 cells by cytokines and lipopolysaccharide (LPS)
bEND. 3 - BCRJ - Cell Line The expression of Peyer's Patch high endothelial receptor for lymphocytes, the mucosal vascular addressin (MAdCAM-1) and E-selectin can be induced on bEnd 3 cells by cytokines and lipopolysaccharide (LPS) This induction by Tumor Necrosis Factor alpha (TNF alpha), interleukin 1 (IL-1) or LPS is concentration and time dependent
中国科学院典型培养物保藏委员会细胞库 中国科学院上海生命 . . . bEnd 3细胞株是一种小鼠脑血管内皮瘤细胞，它是由内皮瘤小鼠的脑组织中分离获得，经编码多瘤病毒中间T抗原的逆转录病毒转化而永生化。 该细胞被检测到血管性血友病因子的表达及对荧光标记的低密度脂蛋白（LDL）的摄入以确认其具有内皮细胞特性。 bEnd 3细胞株持续表达细胞粘附分子1（ICAM-1），并在LPS、IL-1和TNF-a处理后升高。 代数较早的bEnd 3细胞未受刺激时在表面表达MAdCAM-8，但30代后不再表达。 同时，bEnd 3细胞株于30代前可持续表达血管细胞粘附分子1（VCAM-1），30代后也不再表达。 肿瘤坏死因子α（TNF alpha）可以诱导bEnd 3细胞表达P-选择素，且在30代后表达更强。
Cadmium stimulates the expression of ICAM-1 via NF-κB activation in . . . In the present study, we found that Cd (1–10 μM) can increase the expression of ICAM-1 protein and mRNA in a dose- and time-dependent manner in bEnd 3 cells (Fig 1) From these results, it is suggested that the Cd-induced ICAM-1 induction in brain microvascular endothelium may be associated with BBB breakdown and brain damage