Therapeutic effects of in-vivo radiodynamic therapy (RDT) for lung . . . Radiodynamic therapy (RDT) uses high-energy photon beams instead of visible near-infrared light to treat deep-seated tumors that photodynamic therapy cannot achieve due to the low penetration depth of laser beams The purpose of this study is to
Oxygen-Independent Radiodynamic Therapy: Radiation-Boosted . . . Radiodynamic therapy (RDT) has emerged as a promising modality for cancer treatment, offering notable advantages such as deep tissue penetration and radiocatalytic generation of oxygen free radicals
Bioorthogonal Coordination Polymer Nanoparticles with Aggregation . . . Taking advantage of aggregation-induced emission (AIE) photosensitizers with bright fluorescence and efficient singlet oxygen production in the aggregate state, Hf-AIE coordination polymer nanoparticles (CPNs), which show both strong RT and RDT effect under X-ray irradiation, are developed
Radiodynamic therapy promises improving cancer treatment Advances in radiodynamic therapy allows for increased tumoricidal capabilities while limiting toxicities to healthy tissues It has the potential to achieve increased conformality in the treatment of cancer, paving the way for new advances in precision medicine
Introduction to 5-Aminolevulinic Acid-Protoporphyrin IXMediated . . . Photodynamic Therapy (PDT) is a light-based method that uses photo-reactive molecules, such as protoporphyrin IX (PpIX), to ablate tumors Recently, PpIX was shown to act as a radio-reactive molecule by enhancing generation of Reactive Oxygen Species (ROS) upon X-ray irradiation
Radiodynamic Therapy with Acridine Orange Is an Effective Treatment for . . . Acridine orange is a photosensitizing molecule that accumulates in acidic compartments After photo- or radiodynamic activation (AO-PDT or AO-RDT), acridine orange can induce lysosomal-mediated cell death, and we explored AO-RDT as an acid-targeted anticancer therapy for bone metastases
Low-dose X-ray radiodynamic therapy solely based on gold nanoclusters . . . Background: Radiodynamic therapy (RDT) is an emerging novel anti-cancer treatment based on the generation of cytotoxic reactive oxygen species (ROS) at the lesion site following the interaction between low-dose X-ray and a photosensitizer (PS) drug
Investigation of the Mechanisms of Radio-Dynamic Therapy Purpose: Photodynamic therapy (PDT) uses light-activated drugs to treat diseases ranging from cancer to age-related macular degeneration and antibiotic-resistant infections The finite penetration depth of light has limited the clinical application of PDT