RCSB PDB - 9ML8: Crystal structure of the SARS-CoV-2 RBD in complex . . . Broad immune responses are needed to mitigate viral evolution and escape To induce antibodies against conserved receptor-binding domain (RBD) regions of SARS-like betacoronavirus (sarbecovirus) spike proteins that recognize SARS-CoV-2 variants of concern and zoonotic sarbecoviruses, we developed mosaic-8b RBD nanoparticles presenting eight sarbecovirus RBDs arranged randomly on a 60-mer
Crystal structure of SARS-CoV-2 spike receptor-binding . . . - RCSB PDB A new and highly pathogenic coronavirus (severe acute respiratory syndrome coronavirus-2, SARS-CoV-2) caused an outbreak in Wuhan city, Hubei province, China, starting from December 2019 that quickly spread nationwide and to other countries around the world 1-3 Here, to better understand the initial step of infection at an atomic level, we determined the crystal structure of the receptor
2DD8 - RCSB PDB The severe acute respiratory syndrome coronavirus (SARS-CoV, or SCV), which caused a world-wide epidemic in 2002 and 2003, binds to a receptor, angiotensin-converting enzyme 2 (ACE2), through the receptor-binding domain (RBD) of its envelope (spike, S) glycoprotein