EMCrit 380 - Acid Base Part VIII - Tris-Hydroxymethyl Aminomethane . . . Tris-Hydroxymethyl Aminomethane (THAM or tromethamine) is an amino alcohol that acts as a buffer base that unlike NaBicarb doesn't increase Na or release CO2–it actually lowers PaCO2 Sounds great, huh? It is unfortunately expensive and has some other issues we will discuss
Tris - Wikipedia Medical Tris (usually known as THAM in this context) is used as alternative to sodium bicarbonate in the treatment of metabolic acidosis [16][17]
Tromethamine (THAM) Discontinuation - Stanford Health Care THAM is often used in place of sodium bicarbonate because THAM lacks the carbon-dioxide producing effects of bicarbonate THAM is capable of buffering both metabolic and respiratory acids which leads to an increase in extracellular and intracellular pH without carbon dioxide generation
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Pfizer Tham Solution (tromethamine injection) should be administered slowly and in amounts sufficient only to correct the existing acidosis, and to avoid overdosage and alkalosis
THAM (tromethamine injection) | Pfizer Medical - US THAM (tromethamine injection) medication page for healthcare professionals to search for scientific information on Pfizer medications Also find the prescribing information, announcements, resources, and channels to connect with Pfizer Medical
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