EMCrit 380 - Acid Base Part VIII - Tris-Hydroxymethyl Aminomethane . . . Tris-Hydroxymethyl Aminomethane (THAM or tromethamine) is an amino alcohol that acts as a buffer base that unlike NaBicarb doesn't increase Na or release CO2–it actually lowers PaCO2 Sounds great, huh? It is unfortunately expensive and has some other issues we will discuss
Tris - Wikipedia Tris, or tris (hydroxymethyl)aminomethane, or known during medical use as tromethamine or THAM, is an organic compound with the formula (HOCH 2) 3 CNH 2 It is extensively used in biochemistry and molecular biology as a component of buffer solutions [2] such as in TAE and TBE buffers, especially for solutions of nucleic acids
Tromethamine (THAM) Discontinuation - Stanford Health Care Tromethamine (tris-hydroxymethyl aminomethane; also called THAM) has been discontinued by the manufacturer There is no other manufacturer that produces THAM THAM has intermittently been on back order for the past several months It was just recently discontinued by the only manufacturer, Pfizer (Hospira), in the United States as of May 2016
What is Tham? - GoodRx Learn about Tham (Tromethamine), dosing, proper use and what to know before beginning treatment
Tham: Indications, Side Effects, Warnings - Drugs. com It is used to treat or prevent acid problems in the blood What do I need to tell my doctor BEFORE I take Tham? For all patients taking Tham (tromethamine): If you have an allergy to tromethamine or any other part of Tham (tromethamine)
Tris-Hydroxymethyl Aminomethane in Critically Ill Adults: A . . . - LWW Tris-hydroxymethyl aminomethane (THAM) is an amino alcohol used clinically to buffer acid loads and raise pH in acidotic conditions Unlike sodium bicarbonate, which increases plasma sodium levels with use and produces carbon dioxide (CO 2) as part of the buffering process, THAM does neither