Polymeric Iodophors: Preparation, Properties, and Biomedical . . . For example, the effects of the iodophor polyvinylpyrrolidone (PVP)–iodine were studied in bacterial cells by electron microscopy and biochemical methods and were found to include rapid separation of the cytoplasm, nucleotide coagulation, and loss of enzymatic activities
Topical iodophor preparations: Chemistry, microbiology, and clinical . . . Of the seven iodine forms, a bactericidal effect is only attributed to molecular iodine (I2), hypoiodous acid (HOI), and the iodine cation (H2O+I) The polyvinylpryrrolidone portion itself has no bactericidal effect, but owing to its affinity for cell membranes is able to deliver the iodophor preparation to the target
Iodophor - an overview | ScienceDirect Topics Iodophors are substances that have elemental iodine attached to a high-molecular-weight moiety As a general rule, iodophors enhance the bactericidal activity of iodine Iodophors are found in solutions, ointments, and surgical scrubs The most common iodophor, povidone-iodine (Betadine), is an iodine molecule linked to polyvinylpyrrolidone
Increased bactericidal activity of dilute preparations of povidone . . . Recent confirmation of intrinsic bacterial contamination of 10% povidone-iodine solution has raised questions regarding the bactericidal mechanism of iodophors and the possibility for survival of vegetative bacterial cells in iodophor solutions
Iodophor – Knowledge and References – Taylor Francis An iodophor is a formulation that releases iodine and is carried by a carrier It has a paradoxical reaction where low concentrations deliver more free iodine to the target, enhancing its bactericidal effect
Povidone Iodine: Properties, Mechanisms of Action, and Role in . . . PVP-I is a water-soluble iodophor (or iodine-releasing agent) that consists of a complex between iodine and a solubilizing polymer carrier, polyvinylpyrrolidone (23, 24) In aqueous solution, a dynamic equilibrium occurs between free iodine (I 2), the active bactericidal agent, and the PVP-I-complex
Topical iodophor preparations: Chemistry, microbiology, and clinical . . . Of the seven iodine forms, a bactericidal effect is only attributed to molecular iodine (I 2), hypoiodous acid (HOI), and the iodine cation (H 2 O+I) The polyvinylpryrrolidone portion itself has no bactericidal effect, but owing to its affinity for cell membranes is able to deliver the iodophor preparation to the target
Comparison of the disinfection effect of iodophor at two different . . . Iodophor is an amorphous conjugate of elemental iodine and polyvinylpyrrolidone, which is purple-black It is a widely-used bactericidal disinfectant in medical treatment and can kill bacteria in vegetative form, fungi and some viruses [4, 5]
BACTERICIDAL EFFECT OF SOLID IODOPHOR FOR OPERATION STERILIZATION Objective\ To study bactericidal effect of solid iodophor in operation sterilization \ Methods\ Bactericidal effect of different concentrations of iodophor in solution were detected and the results were compared with the bactericidal effect of iodine tincture, ethyl alcohol, isopropyl alcohol \
Efficacy of low-concentration iodophors for germicidal hand washing . . . The efficacy of iodophor germicides containing different concentrations of available iodine against transient (inoculated) bacteria and the natural hand microflora was compared with chlorhexidine gluconate (2 and 4%) liquid detergent (Hibitane), non-germicidal soap and a tap water rinse
Povidone–iodine: use in hand disinfection, skin preparation and . . . Manufacturer’s data show that iodophors are bactericidal, virucidal, fungicidal and tuberculocidal but are not sporicidal at recommended use dilutions (11) Several in vitro studies have investigated the antimicrobial activity of povidone–iodine against different strains of bacteria
Iodophor - an overview | ScienceDirect Topics Iodophors are bactericidal and virucidal Their antibacterial activity does not persist for long periods on skin or in tissues, so frequent reapplication is required Iodophors are relatively nontoxic and nonirritating