Pathology Outlines - Lymphadenoma Salivary glands - Lymphadenoma Benign, encapsulated, solid and cystic (Mod Pathol 2012;25:26) Nests and islands of benign squamous cells, often lining a cyst; epithelial nests have focal sebaceous differentiation
Pathology Outlines - Cutaneous lymphadenoma Skin nonmelanocytic tumor - Cutaneous lymphadenoma This website is intended for pathologists and laboratory personnel but not for patients
Pathology Outlines - Lymphoepithelioma-like carcinoma Skin nonmelanocytic tumors - Lymphoepithelioma-like carcinoma With Diagnostic criteria: Well circumscribed lobules, nests or small aggregates of large, cohesive, epithelioid cells closely associated with a dense, mixed T and B lymphocytic and plasmacytic infiltrate (Rare Tumors 2013;5:e47)
Pathology Outlines - Sebaceous adenoma Benign neoplasm composed of mature sebaceous lobules with expansion of germinative basaloid cell layers at the periphery; associated with Muir-Torre syndrome, especially when it arises outside the head and neck region
Pathology Outlines - Lymphoepithelial sialadenitis Lymphadenoma: Well circumscribed (Virchows Arch 2012;460:467) Even distribution of uniformly sized and shaped epithelial components within lymphoid stroma Absence of lymphoepithelial lesions Chronic sialadenitis: Fibrosis Associated with sialolithiasis Absence of lymphoepithelial lesions Tumor associated lymphoid proliferation (TALP):
Pathology Outlines - Lymphoepithelial cyst Unilocular or multilocular cysts that appear in the salivary glands mainly parotid gland Maybe: HIV related as part of diffuse infiltrative lymphocytosis syndrome (DILS) Non HIV related and associated with autoimmune disease (e g Sjögren syndrome)
Pathology Outlines - Sebaceoma Dermal based tumor with rare epidermal attachments Consists of variably sized, discrete nodules that lack lobular organization architecture (Am J Dermatopathol 1984;6:7, Am J Dermatopathol 2002;24:294, Am J Dermatopathol 2001;23:58, J Am Acad Dermatol 1990;22:533)
Pathology Outlines - Dermatopathic lymphadenopathy Mycosis fungoides: Neoplastic T lymphocytes with cerebriform nuclei that demonstrate partial loss of CD7; Lymph node may be involved even if it is not possible to confirm the presence of atypical T cells by morphology or immunophenotyping; therefore, TCR clonality assay is always required in patients with primary cutaneous lymphoproliferative disorder where regional lymph nodes show
Pathology Outlines - Squamous cell carcinoma Often component or coexisting with other tumors: carcinosarcoma, epidermoid cyst, epithelial myoepithelial carcinoma, malignant mixed tumor, mucoepidermoid carcinoma, sarcomatoid carcinoma, salivary duct carcinoma, sebaceous lymphadenoma, Warthin tumor (Mod Pathol 2002;15:724)