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Sequestrum - Wikipedia A sequestrum (plural: sequestra) is a piece of dead bone [1] that has become separated during the process of necrosis from normal or sound bone It is a complication (sequela) of osteomyelitis The pathological process is as follows: The sequestra are surrounded by sclerotic bone which is relatively avascular (without a blood supply)
Bony sequestrum | Radiology Reference Article - Radiopaedia. org A bony sequestrum (pl sequestra) is a piece of devascularised bone that becomes separated from the remainder of the bone in chronic osteomyelitis and acts as a nidus for ongoing infection 1 In the course of the inflammatory response in an infected bone, there is increased osteoclastic activity resulting in increased bone breakdown 2
Bony sequestrum: a radiologic review - PubMed According to a pathological definition, a bony sequestrum is defined as a piece of devitalized bone that has been separated from the surrounding bone during the process of necrosis
Involucrum vs. Sequestrum — What’s the Difference? Involucrum is new bone formation around a sequestrum, often in response to infection, while sequestrum refers to a piece of lost bone that has become separated from healthy bone due to infection or injury
Sequestration and Involucrum - Orthopedic Clinics Sequestration is an infection-induced avascular necrosis of the diaphysis and or metaphysis of bone The body’s acute phase response calls on cells, toxins, and matrices to trap and destroy microorganisms
Chronic Osteomyelitis: Sequestrum - Museum of Pathology - Monash University This is a sequestrum consisting of dead avascular osseous tissue, the lacunae of which have lost their osteoblasts Sequestrum formation is a complication of chronic osteomyelitis The bone infarction results from loss of the blood supply to a segment of bone, due to the inflammatory process
Sequestrum – Knowledge and References – Taylor Francis A sequestrum is a piece of bone that has died due to ischaemic necrosis, often resulting from an acute infection It may appear on a follow-up X-ray weeks or months after the onset of the infection and can lead to chronic infection and a draining sinus