Understanding Your Genetic Test Results - Susan G. Komen® Genetic test results show if you have a BRCA1, BRCA2 (BRCA1 2) or other inherited gene mutation related to breast cancer For some people with breast cancer, test results help guide treatment There are 3 possible results: Benign or likely benign variant (the test is negative, meaning the results are normal) The test shows normal findings with
BRCA Testing for Breast Ovarian Cancer Risk: Procedure Results BRCA testing looks for abnormal changes in the BRCA1 and BRCA2 genes A positive test result means you have a higher-than-average risk of developing breast, ovarian and other cancers Knowing you have a BRCA gene mutation also means you can take steps to lower your risk and help prevent cancer
BRCA Gene Changes: Cancer Risk and Genetic Testing A positive test result indicates that a person has a harmful change in BRCA1 or BRCA2 (these are typically called “pathogenic” or “likely pathogenic” variants on laboratory test reports) and has an increased risk of developing certain cancers However, a positive test result cannot tell whether or when the tested individual will develop
BRCA gene test for breast and ovarian cancer risk - Mayo Clinic The BRCA gene test looks for DNA changes that increase the risk of breast cancer and ovarian cancer It uses a sample of blood or saliva to look for the changes DNA is the genetic material inside cells It holds the instructions, called genes, that tell cells what to do Results The results of a BRCA gene test may take a few weeks to come
How to Interpret BRCA Test Results | iD. BRCA The results of genetic tests are not always straightforward, which often makes them challenging to interpret In a clinical setting, the main goal of testing is to determine whether the patient carries a pathogenic or likely pathogenic variant, as this knowledge can influence the care and treatment of the patient as well as the risk to other
When to Worry About BRCA Gene Testing Results BRCA gene testing results: What are the possibilities? It may take a few weeks for your genetic test results to come back Once they’re in, you’ll likely discuss the results or meet with your genetic counselor or provider to review them Your genetic test results could be:
Gene test interpretation: BRCA1 and BRCA2 - UpToDate Extent of testing – Most laboratories perform comprehensive sequencing of the BRCA1 and BRCA2 genes; however, it is important to determine whether the entire gene, coding regions, or selected variants were evaluated Comprehensive testing can identify thousands of variants, including many that are clearly established as pathogenic or benign
BRCA Genetic Test - Understand the Test Your Results - MSD Manuals Most results are described as negative, uncertain, or positive, and typically mean the following: A negative result means no BRCA gene mutation was found, but it doesn't mean you won't ever get cancer ; An uncertain result means some kind of BRCA gene mutation was found, but it may or may not be linked with an increased cancer risk You may need more tests and or monitoring if your results