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  • Is It Safe To Mix Cymbalta and Weed? - Marijuana Doctors
    Smoking marijuana while taking Cymbalta is not recommended without consulting your doctor The combination may increase the risk of side effects like dizziness, confusion, and impaired motor skills It’s important to monitor your symptoms closely if you decide to use both
  • Cannabis and Cymbalta Interactions Checker - Drugs. com
    Using cannabis (Schedule I substance) together with DULoxetine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination
  • Marijuana and Antidepressants: Are They Safe to Consume Together?
    A 2020 article published in Frontiers provides some evidence that both CBD and THC may increase the amount of serotonin available in the brain, and marijuana has been shown to contain numerous stress-reducing and mood-enhancing terpenes, which may help treat depression
  • How does weed impact the effectiveness of antidepressants?
    Cymbalta is the brand name for duloxetine, a serotonin-noradrenaline reuptake inhibitor This means that consuming products containing THC could increase or decrease the amount of Cymbalta in
  • Potential Pharmacokinetic Drug-Drug Interactions between Cannabinoids . . .
    There is evidence that coadministration of duloxetine with CYP1A2 and CYP2D6 inhibitors increased duloxetine levels As stated before, CBD is an inhibitor of CYP1A2 and THC, CBD, and CBN inhibit CYP2D6, so if cannabinoids are used as a concomitant medication, an increase in duloxetine plasma levels may be seen
  • Cannabis and Antidepressants: Side Effects and Risks - MentalHealth. com
    Some SNRIs, like duloxetine, is metabolized through the liver and eliminated from the body through different enzymes (CYP1A2) Cannabinoids can interfere with the enzyme, increasing the amount of duloxetine in the blood and a higher likelihood of side effects
  • What to Know About Weed and Antidepressants - Bezzy Depression
    With other antidepressants, like duloxetine (Cymbalta, Irenka) and amitriptyline, weed can also have the opposite effect on your metabolism Weed may make your body metabolize these antidepressants more quickly than your dosage calls for, leaving medication levels too low
  • What Is Duloxetine? How It Works, Its Uses, and Interactions with Cannabis
    Duloxetine, often known by the brand name Cymbalta, is a prescription medication classified as a serotonin-norepinephrine reuptake inhibitor (SNRI) It affects the brain’s chemical messengers, helping to regulate mood and pain perception
  • Marijuana and Antidepressants: Potential Interactions
    SNRIs like Duloxetine (Cymbalta) and Venlafaxine (Effexor XR) also have a low to moderate interaction risk with marijuana However, some users may feel drowsy and dizzy when combining marijuana and antidepressants in this category





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