digitalin
毛地黃苷; 洋地黃甙
毛地黃□; 洋地黃□
digitalin n 1 :
a powerful cardiac stimulant obtained from foxglove [
synonym :
{
digitalis }, {
digitalis glycoside }, {
digitalin }]
digitalin \
dig "
i *
ta `
lin \,
n . [
Cf .
F .
digitaline .]
(
a ) (
Medicine ,
Pharmacy )
Any one of several extracts of foxglove ({
Digitalis }),
as the "
French extract ,"
the "
German extract ,"
etc .,
which differ among themselves in composition and properties .
Both {
Digitalis lanata }
and {
Digitalis purpurea }
have been used to prepare such extracts .
(
b ) (
Chem .)
the distinctive chemical substance ,
a steroid glycoside ,
which is the essential ingredient of the extracts of foxglove .
It is a white ,
crystalline substance ({
C36H56O14 }),
and is a 3 -
substituted diglucoside of a steroid .
It is a powerful cardiac stimulant and is used as a cardiotonic for treatment of certain heart conditions ,
such as congestive heart failure .
Chemically it is (
3 [
beta ],
5 [
beta ],
16 [
beta ])-
3 -[
6 -
Deoxy -
4 -
O -[
beta ]-
D -
glucopyranosyl -
3 -
O -
methyl -[
beta ]-
D -
galactopyranosyl )
oxy ]-
14 ,
16 -
dihyroxy -
card -
20 (
22 )-
enolide .
The related compounds {
digitoxin }
and {
digoxin }
are also extracted from the foxglove .
The class of steroid glycosides having cardiotonic properties are refered to as the cardiac glycosides .
--
MI11 Syn :
digitalinum verum ,
Diginorgin ,
Schmiedeberg '
s digitalin ,
digitalis ,
digitalis glycoside . [
1913 Webster PJC ]
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