Hurler syndrome - Wikipedia Hurler syndrome, also known as mucopolysaccharidosis Type IH (MPS-IH), Hurler's disease, and formerly gargoylism, is a genetic disorder that results in the buildup of large sugar molecules called glycosaminoglycans (GAGs) in lysosomes
Hurler syndrome | About the Disease | GARD - Genetic and Rare Diseases . . . Hurler syndrome is the most severe form of mucopolysaccharidosis type 1 (MPS1; see this term), a rare lysosomal storage disease, characterized by skeletal abnormalities, cognitive impairment, heart disease, respiratory problems, enlarged liver and spleen, characteristic facies and reduced life expectancy
MPS I (Hurler Syndrome) - Boston Childrens Hospital What is MPS I (Hurler syndrome)? Mucopolysarcharidosis type I (MPS I) is a rare, inherited disorder MPS I is also known as Hurler syndrome Children with Hurler syndrome have an abnormal accumulation of complex sugars in their cells, which affects many of the systems in their bodies
What Is Hurler Syndrome (MPS I)? - UPMC Childrens Hospital of Pittsburgh What Is Hurler Syndrome (MPS I)? Hurler syndrome is an inherited condition caused by a faulty gene Children with Hurler syndrome lack an enzyme that the body needs to digest sugar Undigested sugar molecules build up in the body, causing progressive damage to the brain, heart, and other organs
Hurler Syndrome - StatPearls - NCBI Bookshelf Hurler syndrome was formerly known as gargoylism It is an inherited lysosomal disorder caused by the absence of alpha-L-iduronidase, an enzyme responsible for the degradation of glycosaminoglycans (GAGs or mucopolysaccharides)
Hurler Syndrome - Causes, Symptoms, Diagnosis, and Treatment Hurler Syndrome is a complex genetic disorder that requires early diagnosis and comprehensive management to improve outcomes Understanding the causes, symptoms, and treatment options is crucial for affected individuals and their families