Protamine sulfate - Wikipedia Protamine sulfate is usually administered to reverse the large dose of heparin administered during certain surgeries, especially heart surgery where anti-coagulation is necessary to prevent clot formation within the cardiopulmonary bypass pump apparatus
Protamine - StatPearls - NCBI Bookshelf Protamine is a medication used to reverse and neutralize the anticoagulant effects of heparin Protamine is the specific antagonist that neutralizes heparin-induced anticoagulation
What’s fishy about protamine? Clinical use, adverse reactions, and . . . Protamines are histones, highly basic arginine-rich polypeptides that exist in nature to provide structural integrity to DNA in cell nuclei Protamine is a heterogeneous mixture of highly basic molecules due to the presence of up to 70% arginine and other basic amino acids [1]
Protamine - Wikipedia Protamines are small, arginine -rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation via genomic DNA compaction and stabilization