Can angiotensin-converting enzyme inhibitors impact cognitive . . . Studies have revealed reduced rates of cognitive decline, in elderly patients, who were treated with centrally active angiotensin-converting enzyme inhibitors (ACE-Is) (that have an ability to cross the blood–brain barrier)
The role of ACE inhibitors and ARBs in preserving cognitive . . . The primary hypertension treatments, angiotensin receptor blockers, and angiotensin-converting enzyme inhibitors, exhibit neuroprotective properties However, observational studies suggest that they may independently contribute to cognitive decline and dementia
Angiotensin-Converting Enzyme Inhibitors and Cognitive . . . Using a large, population-based cohort, we aimed to determine (1) whether ACE inhibitors as a class, compared with other anti-HTN agents, confer a lower risk of incident dementia, cognitive decline, or incident disability in instrumental activities of daily living (IADLs) among older adults with HTN, and (2) whether there is a difference
Initiation of ARB- vs ACEI-Based Antihypertensive Medication . . . Another study by the SPRINT research group looking at the effect of the randomized intervention on cognitive decline (based on MoCA scores) did not find that rates of cognitive decline differed between the intensive and standard BP control groups (difference of <0 01 points, 95% CI −0 05 to 0 04) 19
ACE Inhibitors May Slow Cognitive Decline - Medscape Centrally acting angiotensin-converting enzyme inhibitors (CACE-Is) reduce the rate of cognitive decline in patients with dementia, regardless of blood pressure levels at the time of their