Variant of Uncertain Significance (VUS) When analysis of a patient’s genome identifies a variant, but it is unclear whether that variant is actually connected to a health condition, the finding is called a variant of uncertain significance (abbreviated VUS)
What to do if your genetic test finds a variant of uncertain . . . But sometimes, you might not get a clear “yes” or “no ” You might just get a “maybe ” “That’s what you’ll hear if you have a variant of uncertain significance, or VUS for short,” says Sara Wofford, a genetic counselor at MD Anderson The Woodlands
VUS Variant of Uncertain Significance for cancer patients . . . Some people, like you, have a Variant of Uncertain Significance (VUS) which is a genetic change that the laboratory cannot interpret VUS cannot be categorized as potentially disease causing or harmless because the meaning of this type of genetic change is not yet known
Understanding genetic variants of uncertain significance - PMC Variants with insufficient or conflicting evidence supporting disease association, such that they cannot be classified as ‘pathogenic likely pathogenic’, nor as ‘benign likely benign’, are VUSs The presence of a VUS, even in a relevant gene or chromosome, does not confirm a genetic diagnosis
Assessing a Variant of Uncertain Significance (VUS) Figuring out if a VUS falls more on the benign or pathogenic side is the first step in determining how to discuss it with a patient and whether to pursue further investigation
Teach English At VUS For one of the best English teaching jobs in Vietnam, look no further than VUS VUS is the leader in the English Language Training (ELT) in Vietnam with millions of learners enrolling for its courses since its foundation