Indole - Wikipedia In the 1930s, interest in indole intensified when it became known that the indole substituent is present in many important alkaloids, known as indole alkaloids (e g , tryptophan and auxins), and it remains an active area of research today
Indole | C8H7N | CID 798 - PubChem Indole | C8H7N | CID 798 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety hazards toxicity information, supplier lists, and more
Indole | Aromatic, Biosynthesis, Metabolism | Britannica Indole, first isolated in 1866, has the molecular formula C 8 H 7 N, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered
What Are Indoles, and Why Are They Important for Health? Key Takeaways Indoles have antioxidant, anti-inflammatory, and detoxification-supporting effects Including indole-rich foods in the diet, such as cruciferous vegetables, leafy greens, fruits, and legumes, can help optimize intake of this compound
Indoles - Chemistry Online Indole is a weak acid (with a value of pKa = 16 97), with an acidity comparable to pyrrole, and to aliphatic alcohols It can be converted to the N -sodium derivative, in liquid ammonia, or with sodium hydride (NaH) in an organic solvent
Indole - an overview | ScienceDirect Topics Presence of an indole nucleus in amino acid tryptophan makes it prominent in phytoconstituents such as perfumes, neurotransmitters, auxins (plant hormones), indole alkaloids, and so on The interesting molecular architecture of indoles makes them suitable candidates for drug development
Synthesis, Reactions and Medicinal Uses of Indole Fischer – indole synthesis - Indoles can be made by adding two or three substitutes to this molecule An arylhydrazine is heated with an aldehyde or ketone, then the resulting arylhydrazone is rearranged with acid to give an indole with a loss of ammonia
Biomedical Importance of Indoles - PMC The indole nucleus is an important element of many natural and synthetic molecules with significant biological activity This review covers some of the relevant and recent achievements in the biological, chemical and pharmacological activity of