Phenacetin - Wikipedia Phenacetin ( fɪˈnæsɪtɪn ⓘ; acetophenetidin, N- (4-ethoxyphenyl)acetamide[1]) is a pain-relieving and fever-reducing drug, which was widely used following its introduction in 1887 It was withdrawn from medicinal use as dangerous from the 1970s (e g , withdrawn in Canada in 1973, [2] and by the U S Food and Drug Administration in 1983 [3])
Phenacetin | C10H13NO2 | CID 4754 - PubChem Phenacetin | C10H13NO2 | CID 4754 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety hazards toxicity information, supplier lists, and more
Phenacetin: Uses, Interactions, Mechanism of Action - DrugBank Online Phenacetin was the first NSAID and fever reducer to go on the market It acts as an analgesic at the spinal cord as well as a negative inotrope at the heart It can be used to treat subacute rheumatoid arthritis, intercostal neuralgia, and ataxias Metabolised in the body to paracetamol
Phenacetin - an overview | ScienceDirect Topics Phenacetin, a painkiller, was the world’s first synthetic pharmaceutical drug It was one of the first painkillers that was not derived from opium while at the same time being absent of anti-inflammatory qualities Phenacetin was developed in 1878 by an American chemist, Harmon Northrop Morse
Phenacetin and Analgesic Mixtures Containing Phenacetin Phenacetin and analgesic mixtures containing phenacetin were administered in tablet and capsule form Until 1983, phenacetin was used in over-the-counter remedies for pain and fever; however, it no longer is used in drug products in the United States
Phenacetin: Uses, Dosage, Side Effects, Food Interaction FAQ Phenacetin was the first NSAID and fever reducer to go on the market It acts as an analgesic at the spinal cord as well as a negative inotrope at the heart It can be used to treat subacute rheumatoid arthritis, intercostal neuralgia, and ataxias
What is Phenacetin Powder Used For? - Salispharm Phenacetin powder, a compound with a complex and controversial history in the pharmaceutical industry, was once a widely used analgesic and antipyretic medication Discovered in the late 19th century, phenacetin quickly gained popularity for its effectiveness in relieving pain and reducing fever
Phenacetin | EBSCO Research Starters Phenacetin is an analgesic and antipyretic that was first introduced in 1887 Originally used for pain relief and fever reduction, it has been linked to serious health risks, including urothelial neoplasms, particularly transitional cell carcinoma of the renal pelvis and bladder
Phenacetin: pharmacokinetics, mechanism of action and clinical . . . Phenacetin is an analgesic and antipyretic drug with distinct pharmacokinetic characteristics It is absorbed orally and metabolized extensively to paracetamol, which has good bioavailability Paracetamol undergoes metabolism and is excreted primarily as glucuronide and sulphate conjugates in urine
Phenacetin = 98. 0 HPLC 62-44-2 - MilliporeSigma Phenacetin ≥98 0% (HPLC); CAS Number: 62-44-2; EC Number: 200-533-0; Synonyms: 1-Acetyl-p-phenetidin,4′-Ethoxyacetanilide,N-(4-Ethoxyphenyl)acetamide,p-Acetophenetidide,Acetophenetidin; Linear Formula: CH3CONHC6H4OC2H5 at Sigma-Aldrich
Phenacetin (Acetophenetidin) | COX-3 Inhibitor - MedChemExpress Phenacetin (Acetophenetidin) is a non-opioid analgesic antipyretic agent Phenacetin is a selective COX-3 inhibitor Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats
PHENACETIN - Pharmaceuticals - NCBI Bookshelf Phenacetin was used as an analgesic and fever-reducing drug in both human and veterinary medicine for many years It was introduced into therapy in 1887 and was extensively used in analgesic mixtures until it was implicated in kidney disease (nephropathy) due to abuse of analgesics
The Versatility and Historical Significance of Phenacetin Phenacetin, an organic compound with a fascinating history, has stood as a hallmark in the realm of pain management Renowned for its effectiveness in alleviating mild to moderate pain and reducing fevers, phenacetin has held a significant role in pharmaceuticals
Phenacetin - an overview | ScienceDirect Topics Phenacetin refers to an analgesic and fever-reducing drug that was previously used in both human and veterinary medicine However, it was withdrawn from the market due to its association with kidney disease caused by the abuse of analgesics