Mucin - Wikipedia Mucin genes encode mucin monomers that are synthesized as rod-shaped apomucin cores that are post-translationally modified by exceptionally abundant glycosylation
Mucin - an overview | ScienceDirect Topics Mucin serves as a pronucleating agent in experimental and human gallstone disease, and the hydrophobic binding sites in the polypeptide core of mucin may provide a favorable environment for nucleation of cholesterol monohydrate from supersaturated bile
Mucin | definition of mucin by Medical dictionary Glycoprotein, rich in carbohydrates, produced by the goblet cells and the subsurface vesicles of the conjunctiva which forms the basis of the mucous layer of the precorneal film
Mucins in cancer: function, prognosis and therapy - PMC Epithelia are protected from adverse conditions by a mucous barrier The secreted and transmembrane mucins that constitute the mucous barrier are largely unrecognized as effectors of carcinogenesis However, both types of mucins are intimately involved in inflammation and cancer
Mucins - Laboratory Notes By forming a hydrated, slippery layer, mucins help maintain tissue integrity, facilitate the movement of materials, and act as a first line of defense against pathogens and environmental stressors
Mucus and Mucins - Colorado State University Mucins are a family of large, heavily glycosylated proteins Although some mucins are membrane bound due to the presence of a hydrophobic membrane-spanning domain that favors retention in the plasma membrane, the concentration here is on those mucins that are secreted on mucosal surfaces and saliva
The role of mucins in gastrointestinal barrier function during health . . . Mucins are the gatekeepers of the mucosal barrier of the gastrointestinal tract and are aberrantly expressed in various gastrointestinal pathologies, including pathogen infection, inflammation, and uncontrolled growth and spread of abnormal cells