Vesicant irritant chemotherapy - HemOnc. org Vesicant: Medication that may causes severe and or irreversible tissue injury and necrosis Irritant: Medication that can cause local inflammatory reactions at the infusion site, which may include: burning, swelling, pain, inflammation, tightness, or phlebitis
Vesicants and Extravasation - Infusion Nurse Blog These two terms defined by the Infusion Nurses Society means: Vesicant - an agent capable of causing blistering, tissue sloughing or necrosis when it escapes from the intended vascular pathway into surrounding tissue
Blister agent - Wikipedia A blister agent (or vesicant) is a chemical compound that causes severe skin, eye and mucosal pain and irritation in the form of severe chemical burns resulting in fluid filled blisters [1]
Extravasation injury from cytotoxic and other noncytotoxic . . . Although the most well-known vesicants are cytotoxic chemotherapy (antineoplastic) drugs (table 1), many other noncytotoxic drugs also have the potential for local toxicity (table 2) The clinical features and management of extravasation injury are reviewed
Understanding Vesicant Drugs and Extravasation Vesicants are a class of drugs known for their potential to cause tissue damage if they leak out of the vein into surrounding tissue Common vesicant agents include certain chemotherapy drugs (e g , doxorubicin, vincristine), antibiotics (e g , vancomycin), and other medications like potassium chloride and calcium chloride